http://purl.org/obo/owlapi/tf_classification_human#5.1
Properties
- subset
- [] Class
- xref
- [] CLASSLINK:http\://www.edgar-wingender.de/class 5.1.html
- label
- [] MADS box factors
- def
- [] "TRANSFAC® class description C0014: Proteins of this class comprise a region of homology. The DNA-binding domain also comprises the dimerization capability. In the DNA-bound dimer (shown for SRF), two antiparallel amphipathic alpha-helices (alpha-I), form a coiled coil and are oriented approximately parallel on the minor groove. These helices make minor and major groove contacts, the N-terminal extensions form minor groove contacts. The bound DNA is bent and wrapped around the protein. It exhibits a compressed minor groove in the center and widened minor groove in the flanks. (PMID 7637780)" []
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