name 6.5 namespace http://purl.org/obo/owlapi/tf_classification_human# parent 6 child 6.5.5 child 6.5.4 child 6.5.1 child 6.5.3 child 6.5.2 subset [] Class xref [] CLASSLINK:http\://www.edgar-wingender.de/class 6.5.html label [] T-Box factors def [] "TRANSFAC® class description C0044: The T domain has originally been discovered in Brachyury (T) the founder member of the T-box family. It encodes a DNA binding domain of about 180 amino acids. X-ray analysis of the T domain showed that it binds as a dimer to a 20 nucleotide partially palindromic sequence. A new type of specific DNA contact is seen, in which a carboxy-terminal helix is deeply embedded into an enlarged minor groove without bending the DNA." []