-  Class
-  Grainyhead domain factors
-  "TRANSFAC class description C0051: Ancient family of factors characterized by a distinct type of DNA binding domain. Members of this class are known in C. elegans, Drosophila, and vertebrates, and involved in the regulation of diverse biological processes (PMID 12888489 and references therein). Majority of the factors are activators, but LBP-9 and CRTR-1 are repressors (PMID 10644752, PMID 11073954). On the basis of sequence similarity, class can be subdivided into the two families: LSF/CP2 and Grainyhead itself (PMID 12888489). Members of this class are characterized by the conserved DNA binding- and oligomerization-associated regions (PMID 12888489). Consensus DNA recognition element of the LSF/CP2 family members represents a direct bipartite repeat CNRG-N(6)-CNRG (PMID 9668115). LSF/CP2 factors bind DNA as homotetramers, Drosophila Elf-1 binds as a dimer (PMID 8349681)."