name	T-lymphocyte
namespace	http://cytomer.bioinf.med.uni-goettingen.de/cell#
parent	 cell 
cellSystemNo []	962
nameMedicineSynonym []	
cellNo []	664
nameEnglishSynonym []	T-cell, thymus-dependent lymphocyte
label [en]	T-lymphocyte
precursorNo []	891
comment [de]	T-Lymphozyten realisieren im Prozess der Immunantwort die zelluläre Immunität (Killerzellen, Helferzellen, Suppressorzellen); T-Lymphozyten tragen ferner auf ihrer Oberfläche die Genprodukte bestimmter Allele des Majorhistokompatibilitätslokus; sie reifen primär im Thymus und werden auch dort selektiert
comment [en]	they develop and mature in the thymus; major function is immune surveillance; they are activated by antigen-presenting cells and react either directly (via cytotoxic T-cells) or indirectly (via helper T-cells, which activate macrophages); they destroy e.g. virus-infected cells, bacterial infected cells; regulatory T-cells regulate or limit immune responses (suppressor T-cells)
ACC []	cy0011313
nameGermanSynonym []	T-Zelle
speciesNo []	86
annotationRemark []	
label [med]	Lymphocytus
label [de]	T-Lymphozyt
differentiatedFrom	lymphocyte
differentiatesInto	helper_T_cell_Th1
isCellOf	http://cytomer.bioinf.med.uni-goettingen.de#medulla_of_thymus
differentiatesInto	suppressor_T_cell
isCellOf	http://cytomer.bioinf.med.uni-goettingen.de#connective_tissue
isCellOf	http://cytomer.bioinf.med.uni-goettingen.de#thymus
isCellOf	http://cytomer.bioinf.med.uni-goettingen.de#secondary_lymphatic_organ
isCellOf	http://cytomer.bioinf.med.uni-goettingen.de#marginal_zone_of_spleen
isCellOf	http://cytomer.bioinf.med.uni-goettingen.de#blood
isCellOf	http://cytomer.bioinf.med.uni-goettingen.de#lymphatic_tissue
differentiatesInto	killer_T_cell
differentiatesInto	helper_T_cell_Th2